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Last updated: 2014/10/27
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APOE polyclonal antibody

  • Catalog # : PAB1286
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against full length native APOE.
  • Immunogen:
  • Native purified human APOE.
  • Host:
  • Goat
  • Reactivity:
  • Human
  • Specificity:
  • This antibody specifically binds to human APOE.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:10000-1:80000)
    ELISA (1:10000-1:80000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, pH 7.2 (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 348
  • Gene Name:
  • APOE
  • Gene Alias:
  • AD2,LPG,MGC1571,apoprotein
  • Gene Description:
  • apolipoprotein E
  • Gene Summary:
  • Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
  • Other Designations:
  • apolipoprotein E3
  • Gene Pathway
  • Related Disease
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