CCL11 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of CCL11 in HeLa cell lysate containing 10, 2.5, or 1 ng of full length recombinant CCL11 with CCL11 polyclonal antibody (Cat # PAB12824) at 1 ug/mL.
Immunocytochemistry
Immunocytochemistry of CCL11 in 293 cells with CCL11 polyclonal antibody (Cat # PAB12824) at 5 ug/mL .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CCL11.
Immunogen
A synthetic peptide corresponding to C-terminus amino acids of human CCL11.
Host
Rabbit
Reactivity
Human
Specificity
The recombinant protein can be used as positive control and monomer and homodimer are detected at approximate 9 and 18 KDa.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot analysis of CCL11 in HeLa cell lysate containing 10, 2.5, or 1 ng of full length recombinant CCL11 with CCL11 polyclonal antibody (Cat # PAB12824) at 1 ug/mL.Immunocytochemistry
Immunocytochemistry of CCL11 in 293 cells with CCL11 polyclonal antibody (Cat # PAB12824) at 5 ug/mL . -
Gene Info — CCL11
Entrez GeneID
6356Protein Accession#
CAB07027Gene Name
CCL11
Gene Alias
MGC22554, SCYA11
Gene Description
chemokine (C-C motif) ligand 11
Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq
Other Designations
eosinophil chemotactic protein|eotaxin|small inducible cytokine A11|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3.
Kitaura M, Nakajima T, Imai T, Harada S, Combadiere C, Tiffany HL, Murphy PM, Yoshie O.
The Journal of Biological Chemistry 1996 Mar; 271(13):7725.
-
CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia.
He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, Busciglio J, Yang X, Hofmann W, Newman W, Mackay CR, Sodroski J, Gabuzda D.
Nature 1997 Feb; 385(6617):645.
Application：Incubated, Recombinant protein.
-
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates.
Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J.
Cell 1996 Jun; 85(7):1135.
-
Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com