GSK3B polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The mouse muscle tissue lysates were resolved onto 10% SDS-PAGE, transferred to NC membrane, and followed by an immunoblotting with GSK3B polyclonal antibody (Cat # PAB12688, lane 1) at 1 : 500, or with a pre-incubation of immunizing peptide (lane 2).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GSK3B.
Immunogen
A synthetic peptide corresponding to C-terminus of human GSK3B.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody recognizes GSK3B.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In TBS, pH 7.2 (BSA, 10% Proclin300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
The mouse muscle tissue lysates were resolved onto 10% SDS-PAGE, transferred to NC membrane, and followed by an immunoblotting with GSK3B polyclonal antibody (Cat # PAB12688, lane 1) at 1 : 500, or with a pre-incubation of immunizing peptide (lane 2).Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — GSK3B
Entrez GeneID
2932Gene Name
GSK3B
Gene Alias
-
Gene Description
glycogen synthase kinase 3 beta
Omim ID
605004Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Other Designations
GSK3beta isoform|glycogen synthase kinase-3 beta
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease.
Kozikowski AP, Gaisina IN, Petukhov PA, Sridhar J, King LT, Blond SY, Duka T, Rusnak M, Sidhu A.
ChemMedChem 2006 Feb; 1(2):256.
-
Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com