The tissue lysate derived from rat brain was immunoprecipitated by CREB1 (phospho S133) polyclonal antibody (Cat # PAB12673), then immuno-blotted by the CREB1 (phospho S133) polyclonal antibody (Cat # PAB12617) at 1 : 500 (lane 1), Lane 2 : negative control.
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
active transcription factor CREB,cAMP-response element-binding protein-1,transactivator protein