The whole cell lysate derived from UV treated Raji cell was separated in 10% SDS-PAGE, transferred onto NC membrane, and immunoblotted by Phospho-BCL2 T56 polyclonal antibody (Cat # PAB12610) at 1 : 500. An immunoreactive band around ~26 kDa is observed.
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq