Western blot analysis of cleaved CYR61 in MDA-MB-231 cell lysate using CYR61 polyclonal antibody (Cat # PAB12525). Photo courtesy of Dr. Lupu's Lab, Northwestern University. Image by Dr. Ingrid Espinoza.
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type.[supplied by OMIM
OTTHUMP00000012303,cysteine-rich heparin-binding protein 61,cysteine-rich, anigogenic inducer, 61