ACSL1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ACSL1.
Immunogen
A synthetic peptide corresponding to amino acids 1-100 of human ACSL1.
Host
Rabbit
Reactivity
Human, Mouse, Primates, Rat
Form
Liquid
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (30% glycerol, 0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ACSL1 in HepG2 whole cell lysates using ACSL1 polyclonal antibody (Cat # PAB12497). -
Gene Info — ACSL1
Entrez GeneID
2180Protein Accession#
P33121Gene Name
ACSL1
Gene Alias
ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Gene Description
acyl-CoA synthetase long-chain family member 1
Omim ID
152425Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq
Other Designations
fatty-acid-Coenzyme A ligase, long-chain 1|fatty-acid-Coenzyme A ligase, long-chain 2|lignoceroyl-CoA synthase|long-chain acyl-CoA synthetase 1|long-chain acyl-CoA synthetase 2|long-chain fatty-acid-coenzyme A ligase 1|palmitoyl-CoA ligase 2|paltimoyl-CoA
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Interactome
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Pathway
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Disease
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Publication Reference
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Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo.
Parkes HA, Preston E, Wilks D, Ballesteros M, Carpenter L, Wood L, Kraegen EW, Furler SM, Cooney GJ.
American Journal of Physiology. Endocrinology and Metabolism 2006 Oct; 291(4):E737.
Application:WB-Ti, Mouse, Mouse liver.
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Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes.
Richards MR, Harp JD, Ory DS, Schaffer JE.
Journal of Lipid Research 2006 Mar; 47(3):665.
Application:WB, Mouse, 3T3-L1 cells.
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Overexpression of acyl-CoA synthetase-1 increases lipid deposition in hepatic (HepG2) cells and rodent liver in vivo.
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