BECN1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against BECN1.
Immunogen
Full length human BECN1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody is specific to Beclin 1.
Form
Liquid
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In antiserum (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of BECN1 in liver lysates using BECN1 polyclonal antibody (Cat # PAB12474). Lane 1 : mouse liver. Lane 2 : human liver. -
Gene Info — BECN1
Entrez GeneID
8678Protein Accession#
Q14457Gene Name
BECN1
Gene Alias
ATG6, VPS30, beclin1
Gene Description
beclin 1, autophagy related
Omim ID
604378Gene Ontology
HyperlinkGene Summary
O
Other Designations
ATG6 autophagy related 6 homolog|beclin 1|beclin 1 (coiled-coil, moesin-like BCL2 interacting protein)|beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
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Interactome
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Pathway
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Disease
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Publication Reference
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Preconditioning of exosomes derived from human olfactory ensheathing cells improved motor coordination and balance in an SCA3/MJD mouse model: A new therapeutic approach.
Yu-Shuan Chen, Horng-Jyh Harn, Zhen-Xiang Hong, Yi-Chen Huang, Yi-Tung Lin, Hui-Xuan Zheng, Pei-Yu Chen, Hsueh-Hui Yang, Peir-Rong Chen, Hsieh-Chih Tsai, Shinn-Zong Lin, Tsung-Jung Ho, Tzyy-Wen Chiou.
European Federation for Pharmaceutical Sciences 2023 Dec; 191:106608.
Application:WB, Human, hOEC, HEK293 cells.
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Consequences of the selective blockage of chaperone-mediated autophagy.
Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM.
PNAS 2006 Apr; 103(15):5805.
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Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21.
Aita VM, Liang XH, Murty VV, Pincus DL, Yu W, Cayanis E, Kalachikov S, Gilliam TC, Levine B.
Genomics 1999 Jul; 59(1):59.
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Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein.
Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B.
Journal of Virology 1998 Nov; 72(11):8586.
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Preconditioning of exosomes derived from human olfactory ensheathing cells improved motor coordination and balance in an SCA3/MJD mouse model: A new therapeutic approach.
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