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- Home > Products > Polyclonal Ab > Human > Apoptosis > BECN1 polyclonal antibody
BECN1 polyclonal antibody
- Catalog # : PAB12472
- Visit Frequency :
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- 100 uL
- USD $ 415
- order now, ship in 5 days
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BECN1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 1-100 of human BECN1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody is specific to human Beclin 1.
- Form:
- Liquid
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy.
Pattingre S, Bauvy C, Carpentier S, Levade T, Levine B, Codogno P.J Biol Chem. 2009 Jan 30;284(5):2719-28. Epub 2008 Nov 23.
- 2.
- Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.
Gulati P, Gaspers LD, Dann SG, Joaquin M, Nobukuni T, Natt F, Kozma SC, Thomas AP, Thomas G.Cell Metab. 2008 May;7(5):456-65.
- 3.
- Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus.
Wang Y, Singh R, Massey AC, Kane SS, Kaushik S, Grant T, Xiang Y, Cuervo AM, Czaja MJ.J Biol Chem. 2008 Feb 22;283(8):4766-77. Epub 2007 Dec 11.
- 4.
- A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells.
Park KJ, Lee SH, Kim TI, Lee HW, Lee CH, Kim EH, Jang JY, Choi KS, Kwon MH, Kim YS.Cancer Res. 2007 Aug 1;67(15):7327-34.
- 5.
- Consequences of the selective blockage of chaperone-mediated autophagy.
Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM.Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5805-10. Epub 2006 Apr 3.
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence
- Entrez GeneID:
- 8678
- Protein Accession#:
- Q14457
- Gene Name:
- BECN1
- Gene Alias:
- ATG6,VPS30,beclin1
- Gene Description:
- beclin 1, autophagy related
- Omim ID:
- 604378
- Gene Ontology:
- Hyperlink
- Other Designations:
- ATG6 autophagy related 6 homolog,beclin 1,beclin 1 (coiled-coil, moesin-like BCL2 interacting protein),beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)
- Gene Pathway
- Related Disease
