SLIRP polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SLIRP in a human liver lysate using SLIRP polyclonal antibody (Cat # PAB124678) at 0.6 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLIRP.
Immunogen
A synthetic peptide corresponding to C-terminus of human SLIRP.
Host
Rabbit
Reactivity
Human, Primates
Specificity
This antibody is specific to SLIRP protein.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SLIRP in a human liver lysate using SLIRP polyclonal antibody (Cat # PAB124678) at 0.6 ug/mL . -
Gene Info — SLIRP
Entrez GeneID
81892Protein Accession#
Q9GZT3Gene Name
SLIRP
Gene Alias
DC23, C14orf156, DC50, PD04872
Gene Description
SRA stem-loop interacting RNA binding protein
Omim ID
610211Gene Ontology
HyperlinkGene Summary
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM
Other Designations
SRA stem-loop-interacting RNA-binding protein, mitochondrial
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Interactome
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Publication Reference
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SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.
Hatchell EC, Colley SM, Beveridge DJ, Epis MR, Stuart LM, Giles KM, Redfern AD, Miles LE, Barker A, MacDonald LM, Arthur PG, Lui JC, Golding JL, McCulloch RK, Metcalf CB, Wilce JA, Wilce MC, Lanz RB, O'Malley BW, Leedman PJ.
Molecular Cell 2006 Jun; 22(5):657.
Application：ChIP, IHC, WB-Ti, Human, Monkey, Mouse, Rat, C2C12, Calu-6, COS-7, HeLa, HT1080, J2E, LNCaP, MCF-7, MDA-MB-468, NIH-3T3, OD9DL, PC3, Rat brain, SK-BR-3,T47D cells, Human breast cancer tissue.
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SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.
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