Rabbit polyclonal antibody raised against synthetic peptide of CXCR4.
Immunogen:
A synthetic peptide corresponding to amino acids at N-terminus of human CXCR4.
Host:
Rabbit
Theoretical MW (kDa):
39.7, 40.2
Reactivity:
Human, Mouse, Rat
Specificity:
Different to the related rat sequence by two amino acids.
Form:
Lyophilized
Purification:
Affinity purification
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2 ug/mL) The optimal working dilution should be determined by the end user.
Store at -20°C on dry atmosphere. After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Western Blot analysis of SLC10A1 expression from cell extracts with CXCR4 polyclonal antibody (Cat # PAB12323). Lane 1 : MCF-7 whole cell lysate. Lane 2 : HeLa whole cell lysate. Lane 3 : Jurkat whole cell lysate. Lane 4 : HT1080 whole cell lysate. Lane 5 : Colo 320 whole cell lysate.
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations:
C-X-C chemokine receptor type 4,CD184 antigen,chemokine (C-X-C motif), receptor 4 (fusin),chemokine receptor 4,fusin,leukocyte-derived seven-transmembrane-domain receptor,lipopolysaccharide-associated protein 3,neuropeptide Y receptor Y3,seven transmembra