Western Blot analysis of SLC10A1 expression from cell extracts with CXCR4 polyclonal antibody (Cat # PAB12323). Lane 1 : MCF-7 whole cell lysate. Lane 2 : HeLa whole cell lysate. Lane 3 : Jurkat whole cell lysate. Lane 4 : HT1080 whole cell lysate. Lane 5 : Colo 320 whole cell lysate.
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
C-X-C chemokine receptor type 4,CD184 antigen,chemokine (C-X-C motif), receptor 4 (fusin),chemokine receptor 4,fusin,leukocyte-derived seven-transmembrane-domain receptor,lipopolysaccharide-associated protein 3,neuropeptide Y receptor Y3,seven transmembra