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Last updated: 2014/11/23
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MMP14 polyclonal antibody

  • Catalog # : PAB12288
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of MMP14.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at C-terminus of human MMP14.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Different from the related mouse sequence by single amino acid.
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    Immunohistochemistry (Frozen sections) (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of MMP14 on formalin fixed, paraffin embedded rat small intestine with MMP14 polyclonal antibody (Cat # PAB12288).
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 4323
  • Gene Name:
  • MMP14
  • Gene Alias:
  • MMP-X1,MT1-MMP,MTMMP1
  • Gene Description:
  • matrix metallopeptidase 14 (membrane-inserted)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq
  • Other Designations:
  • matrix metalloproteinase 14,matrix metalloproteinase 14 (membrane-inserted),membrane type 1 metalloprotease,membrane-type matrix metalloproteinase 1,membrane-type-1 matrix metalloproteinase
  • Gene Pathway
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