Scarb1/Scarb2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of Scarb1/Scarb2 in 80 ug of total mouse liver lysates using Scarb1/Scarb2 polyclonal antibody (Cat # PAB12123). Lane 1 : wild-type mice, Lane 2 : SR-BI deficient mice.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Scarb1/Scarb2.
Immunogen
A synthetic peptide corresponding to amino acids 230-380 of mouse Scarb1/2.
Host
Rabbit
Reactivity
Mouse
Specificity
This antibody is specific to SR-BI and SR-BII.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunocytochemistry (1:50-1:1000)
Immunofluorescence (1:50-1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In antiserum (0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of Scarb1/Scarb2 in 80 ug of total mouse liver lysates using Scarb1/Scarb2 polyclonal antibody (Cat # PAB12123). Lane 1 : wild-type mice, Lane 2 : SR-BI deficient mice.Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — Scarb2
Entrez GeneID
12492Protein Accession#
Q61009 (Gene ID : 20778);O35114 (Gene ID : 12492)Gene Name
Scarb2
Gene Alias
9330185J12Rik, Cd36l2, LGP85, LIMP-2, MLGP85
Gene Description
scavenger receptor class B, member 2
Gene Ontology
HyperlinkGene Summary
O
Other Designations
CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2|LIMP II
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Gene Info — Scarb1
Entrez GeneID
20778Protein Accession#
Q61009 (Gene ID : 20778);O35114 (Gene ID : 12492)Gene Name
Scarb1
Gene Alias
AI120173, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, SR-B1, SR-BI, SRBI, Srb1, mSR-BI
Gene Description
scavenger receptor class B, member 1
Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTMUSP00000026063|scavenger receptor class B type I|scavenger receptor class B1
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Publication Reference
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SR-BI undergoes cholesterol-stimulated transcytosis to the bile canaliculus in polarized WIF-B cells.
Harder CJ, Meng A, Rippstein P, McBride HM, McPherson R.
The Journal of Biological Chemistry 2007 Jan; 282(2):1445.
Application：WB, Human, WIF-B cells.
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Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism.
Kocher O, Yesilaltay A, Cirovic C, Pal R, Rigotti A, Krieger M.
The Journal of Biological Chemistry 2003 Dec; 278(52):52820.
Application：IHC, WB-Ti, Mouse, Liver, Small intestine, Adrenal gland,Testis, Ovary.
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A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver.
Silver DL.
The Journal of Biological Chemistry 2002 Jul; 277(37):34042.
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SR-BI undergoes cholesterol-stimulated transcytosis to the bile canaliculus in polarized WIF-B cells.
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