TRPA1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TRPA1 in human brain membrane fraction with TRPA1 polyclonal antibody at 2 ug/mL (Cat # PAB11992).
Immunohistochemistry
Immunohistochemical staining of TRPA1 on mouse intestine with TRPA1 polyclonal antibody (Cat # PAB11992).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TRPA1.
Immunogen
A synthetic peptide corresponding to amino acids 1-100 of human TRPA1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Immunoaffinity purification
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunohistochemistry (0.5-1 ug/mL)
Western Blot (2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TRPA1 in human brain membrane fraction with TRPA1 polyclonal antibody at 2 ug/mL (Cat # PAB11992).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry
Immunohistochemical staining of TRPA1 on mouse intestine with TRPA1 polyclonal antibody (Cat # PAB11992). -
Gene Info — TRPA1
Entrez GeneID
8989Protein Accession#
O75762Gene Name
TRPA1
Gene Alias
ANKTM1
Gene Description
transient receptor potential cation channel, subfamily A, member 1
Omim ID
604775Gene Ontology
HyperlinkGene Summary
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq
Other Designations
ankyrin-like protein 1|ankyrin-like with transmembrane domains 1
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Interactome
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Publication Reference
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Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue.
Elsa Cortés-Montero, María Rodríguez-Muñoz, María Del Carmen Ruiz-Cantero, Enrique José Cobos, Pilar Sánchez-Blázquez, Javier Garzón-Niño.
International Journal of Molecular Sciences 2020 Dec; 22(1):229.
Application：WB-Ti, Mouse, Mouse cerebral cortex, Mouse dorsal root ganglia,, Mouse spinal cord.
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Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents.
Stenger B, Zehfuss F, Mückter H, Schmidt A, Balszuweit F, Schäfer E, Büch T, Gudermann T, Thiermann H, Steinritz D.
Archives of Toxicology 2015 Sep; 89(9):1631.
Application：WB-Tr, Human, HEK293 cells.
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Bioimaging application of highly luminescent silica-coated ZnO-nanoparticle quantum dots with biotin.
Matsuyama K, Ihsan N, Irie K, Mishima K, Okuyama T, Muto H.
Journal of Colloid and Interface Science 2013 Jun; 399:19.
Application：IF, Mouse, Caco-2 cells, Mouse spinal cord.
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Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
Nagata K, Duggan A, Kumar G, García-Añoveros J.
The Journal of Neuroscience 2005 Apr; 20(16):4052.
Application：IF, WB-Ti, Rat, Peripheral nerve.
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Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue.
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