Rabbit polyclonal antibody raised against recombinant PCNA.
Immunogen:
Recombinant protein corresponding to human PCNA.
Host:
Rabbit
Theoretical MW (kDa):
36
Reactivity:
Human
Form:
Liquid
Purification:
Immunoaffinity purification
Concentration:
Lot specific
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:200) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
Storage Instruction:
Store at 4°C.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
Other Designations:
DNA polymerase delta auxiliary protein,OTTHUMP00000030189,OTTHUMP00000030190,cyclin