Rabbit polyclonal antibody raised against recombinant TNF.
Immunogen:
Recombinant protein corresponding to human TNF.
Host:
Rabbit
Reactivity:
Human
Form:
Liquid
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Recommend Usage:
ELISA (1:200-1:1000) Western Blot (1:100-1:200) Immunocytochemistry (1:200) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 20 mM KH2PO4, 150 mM NaCl, pH 7.2
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
Other Designations:
APC1 protein,OTTHUMP00000029281,OTTHUMP00000037669,TNF superfamily, member 2,TNF, macrophage-derived,TNF, monocyte-derived,cachectin,tumor necrosis factor alpha