BCL2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against a synthetic peptide of BCL2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BCL2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
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Gene Info — BCL2
Entrez GeneID
596Gene Name
BCL2
Gene Alias
Bcl-2
Gene Description
B-cell CLL/lymphoma 2
Omim ID
151430Gene Ontology
HyperlinkGene Summary
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq
Other Designations
B-cell lymphoma protein 2|OTTHUMP00000163680
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Interactome
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Pathway
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Disease
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Publication Reference
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Tioman virus infection in experimentally infected mouse brain and its association with apoptosis.
Yaiw KC, Ong KC, Chua KB, Bingham J, Wang L, Shamala D, Wong KT.
Journal of Virological Methods 2007 Apr; 143(2):140.
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CpG-oligodeoxynucleotide protects immune cells from gamma-irradiation-induced cell death.
Sohn WJ, Lee KW, Choi SY, Chung E, Lee Y, Kim TY, Lee SK, Choe YK, Lee JH, Kim DS, Kwon HJ.
Molecular Immunology 2005 Aug; 43(8):1163.
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Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by Delta12-prostaglandin J2.
Kim BE, Lee JH, Kim HS, Kwon OJ, Jeong SW, Kim IK.
Experimental & Molecular Medicine 2004 Oct; 36(5):444.
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Tioman virus infection in experimentally infected mouse brain and its association with apoptosis.
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