MET (phospho Y1356) polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of MET.
Immunogen
Synthetic phosphopeptide (conjugated with MAPS) corresponding to residues surrounding Y1356 of human MET.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Dot Blot (Peptide)
Dot blot analysis of MET (phospho Y1356) polyclonal antibody (Cat # PAB0536) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. -
Gene Info — MET
Entrez GeneID
4233Protein Accession#
NP_000236;P08581Gene Name
MET
Gene Alias
AUTS9, HGFR, RCCP2, c-Met
Gene Description
met proto-oncogene (hepatocyte growth factor receptor)
Gene Ontology
HyperlinkGene Summary
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
HGF receptor|OTTHUMP00000069168|SF receptor|met proto-oncogene|met proto-oncogene tyrosine kinase|oncogene MET|scatter factor receptor
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
WKYMVm-induced cross-talk between FPR2 and HGF receptor in human prostate epithelial cell line PNT1A.
Cattaneo F, Parisi M, Ammendola R.
FEBS Letters 2013 May; 587(10):1536.
Application:WB-Ce, WB-Tr, Human, PNT1A cells.
-
Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation.
Wong AS, Roskelley CD, Pelech S, Miller D, Leung PC, Auersperg N.
Experimental Cell Research 2004 Sep; 299(1):248.
-
MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, Yamamoto T, Saito Y, Nakamura M.
Molecular and Cellular Biology 2004 Sep; 24(17):7456.
-
Activation of the hepatocyte growth factor (HGF)-Met system in papillary thyroid cancer: biological effects of HGF in thyroid cancer cells depend on Met expression levels.
Mineo R, Costantino A, Frasca F, Sciacca L, Russo S, Vigneri R, Belfiore A.
Endocrinology 2004 Jun; 145(9):4355.
-
WKYMVm-induced cross-talk between FPR2 and HGF receptor in human prostate epithelial cell line PNT1A.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com