Rabbit polyclonal antibody raised against partial recombinant SMAD3.
Immunogen:
Recombinant protein corresponding to amino acids 100-150 of human SMAD3.
Host:
Rabbit
Reactivity:
Bovine, Dog, Human, Monkey, Mouse, Pig, Rat
Form:
Liquid
Recommend Usage:
The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.2% gelatin, 0.05% sodium azide)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Applications
Western Blot (Tissue lysate)
Western blot analysis of SMAD3 in the 1) absence and 2) presence of immunizing peptide in human liver lysate, 3) mouse liver and 4) rat liver. Using SMAD3 polyclonal antibody (Cat # PAB0288) at 0.5 ug/mL .
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq
Other Designations:
MAD, mothers against decapentaplegic homolog 3,SMA- and MAD-related protein 3,SMAD, mothers against DPP homolog 3,mad homolog JV15-2,mad protein homolog,mothers against decapentaplegic homolog 3