Rabbit polyclonal antibody raised against partial recombinant BIRC4.
Immunogen:
Recombinant protein corresponding to amino acids 163-230 of human BIRC4.
Host:
Rabbit
Reactivity:
Gerbils, Human, Mouse, Rat
Form:
Liquid
Recommend Usage:
The optimal working dilution should be determined by the end user.
Storage Buffer:
In serum (0.05% sodium azide)
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Applications
Western Blot (Cell lysate)
Western blot analysis of BIRC4 in various tumor cell lines recombinant BIRC4 polyclonal antibody (Cat # PAB0282) at 1 : 2000.
Western Blot (Recombinant protein)
Western blot analysis of recombinant full-length IAP proteins using polyclonal antibody to BIRC4 polyclonal antibody (Cat # PAB0282) at 1 : 2000. The data shows that the antibody recognizes only BIRC4 and not the other IAP proteins.
Immunohistochemical analysis of BIRC4 in formalin-fixed, paraffin-embedded human breast carcinoma. Using BIRC4 polyclonal antibody (Cat # PAB0282) at 1 : 2000. A-A3, successively higher magnifications of the breast carcinoma tissue section. Hematoxylin-eosin counterstain.
The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. This protein inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. It also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. [provided by RefSeq
Other Designations:
OTTHUMP00000023975,OTTHUMP00000196392,apoptosis inhibitor 3,baculoviral IAP repeat-containing 4,baculoviral IAP repeat-containing protein 4