DIABLO (Human) Recombinant Protein
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Specification
Product Description
Human DIABLO (NP_063940.1, 1 a.a. - 239 a.a.) full-length recombinant protein with His-GST tag expressed in Escherichia coli.
Host
Escherichia coli
Theoretical MW (kDa)
56.1
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 90%
Quality Control Testing
10% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
SDS-PAGE
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Gene Info — DIABLO
Entrez GeneID
56616GeneBank Accession#
NM_019887.4Protein Accession#
NP_063940.1Gene Name
DIABLO
Gene Alias
DIABLO-S, FLJ10537, FLJ25049, SMAC, SMAC3
Gene Description
diablo homolog (Drosophila)
Omim ID
605219Gene Ontology
HyperlinkGene Summary
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq
Other Designations
0610041G12Rik|diablo|direct IAP-binding protein with low pI|mitochondrial Smac protein|second mitochondria-derived activator of caspase
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Interactome
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Disease
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