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EGFR (d747-749/A750P) (Human) Recombinant Protein   BioActive

  • Catalog # : P4816
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  • 100 ug
  • USD $ 1,239
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    Phone : +1-909-992-0619 (new)
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  • Specification
  • Product Description:
  • Human EGFR (NM_005228.3, 672 a.a. - 1210 a.a.) amino acids 747-749 deleted and A750P mutant partial protein expressed in Sf9 cells.
  • Theoretical MW (kDa):
  • 88.799
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purification:
  • GST affinity chromatography
  • Concentration:
  • 0.150 ug/uL
  • Activity:
  • 168 pmol/ug x min
  • Quality Control Testing:
  • 2 ug/lane SDS-PAGE Stained with Coomassie Blue

    QC Testing of P4816
  • Storage Buffer:
  • In 50 mM Hepes, 100 mM NaCl, pH 7.5 (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 1956
  • Gene Name:
  • EGFR
  • Gene Alias:
  • ERBB,ERBB1,HER1,PIG61,mENA
  • Gene Description:
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • Gene Summary:
  • The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
  • Other Designations:
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor
  • Interactome
  • Related Disease
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