IL6 (Human) Recombinant Protein
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Specification
Product Description
Human IL6 (P05231) recombinant protein expressed in Escherichia coli.
Sequence
MPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Host
Escherichia coli
Theoretical MW (kDa)
21
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Endotoxin Level
< 0.1 EU/ug
Activity
The activity is determined by the dose-dependant stimulation of mouse 7TD1 cells and is typcially less than 1 ng/mL.
Quality Control Testing
1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue
Lane 1: non-reducing conditions
Lane 2: reducing conditionsStorage Buffer
Lyophilized from 10 mM acetic acid
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 10 mM HCl, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL6
Entrez GeneID
3569Protein Accession#
P05231Gene Name
IL6
Gene Alias
BSF2, HGF, HSF, IFNB2, IL-6
Gene Description
interleukin 6 (interferon, beta 2)
Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq
Other Designations
interleukin 6
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Interactome
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Pathway
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Disease
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