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Last updated: 2014/11/16

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APOE (Human) Native Protein

  • Catalog # : P4281
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  • Specification
  • Product Description:
  • Human APOE native protein from human plasma.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 34
  • Form:
  • Liquid
  • Preparation Method:
  • Native protein purified from human plasma
  • Purity:
  • ≥ 95% by SDS-PAGE
  • Storage Buffer:
  • In 50 mM NH4HCO3, pH 8.0
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 348
  • Gene Name:
  • APOE
  • Gene Alias:
  • AD2,LPG,MGC1571,apoprotein
  • Gene Description:
  • apolipoprotein E
  • Gene Summary:
  • Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
  • Other Designations:
  • apolipoprotein E3
  • Gene Pathway
  • Related Disease
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