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NTRK2 (Human) Recombinant ProteinBioActive

  • Catalog # : P4241
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  • Specification
  • Product Description:
  • Human NTRK2 (NP_001007098.1, 455 a.a. - end) partial recombinant protein expressed in Sf9 cells.
  • Host:
  • Insect
  • Theoretical MW (kDa):
  • 67
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell (Sf9) expression system
  • Purity:
  • ≥ 80% by SDS-PAGE
  • Activity:
  • The specific activity of TRKB was determined to be 74 nmol/min/mg as per activity assay protocol.
  • Quality Control Testing:
  • SDS-PAGE Result

    QC Testing of P4241
  • Storage Buffer:
  • In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 4915
  • Gene Name:
  • NTRK2
  • Gene Alias:
  • GP145-TrkB,TRKB
  • Gene Description:
  • neurotrophic tyrosine kinase, receptor, type 2
  • Gene Summary:
  • This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • BDNF/NT-3 growth factors receptor,OTTHUMP00000021573,OTTHUMP00000021574,OTTHUMP00000021575,OTTHUMP00000021576,OTTHUMP00000021577,tyrosine kinase receptor B
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