Human IL8 (P10145) (77 amino acids) partial recombinant protein expressed in Escherichia coli.
Theoretical MW (kDa):
8.4
Form:
Lyophilized
Preparation Method:
Escherichia coli expression system
Purity:
≥ 98% by SDS-PAGE and HPLC
Endotoxin Level:
< 0.1 ng/ug
Activity:
The ED50 was determined by its chemotaxis of hCXCR2 transfected mouse BaF/3 cells is less than 0.5 ng/mL, corresponding to a specific activity of 2.0 x 106 units/mg.
Storage Buffer:
Lyophilized from 20 mM PBS, 50 mM NaCl, pH 7.4
Storage Instruction:
Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at 4°C for 1 week or -20°C for longer. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq
Other Designations:
T cell chemotactic factor,beta-thromboglobulin-like protein,chemokine (C-X-C motif) ligand 8,emoctakin,granulocyte chemotactic protein 1,lymphocyte-derived neutrophil-activating factor,monocyte-derived neutrophil chemotactic factor,neutrophil-activating p