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FGF1 (Human) Recombinant ProteinBioActive

  • Catalog # : P3964
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  • Specification
  • Product Description:
  • Human FGF1 (P05230, 140 amino acids) partial recombinant protein expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 15.8
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • ≥ 98% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug
  • Activity:
  • The ED50 was determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is < 10 ng/mL, corresponding to a specific activity of > 1 x 105 units/mg.
  • Quality Control Testing:
  • SDS-PAGE Result

    QC Testing of P3964
  • Storage Buffer:
  • Lyophilized from 0.1 M NaCl, 10 mM Tris, pH 7.6
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 10 mM Tris, store at 4°C for 1 week or -20°C for longer.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 2246
  • Gene Name:
  • FGF1
  • Gene Alias:
  • AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1
  • Gene Description:
  • fibroblast growth factor 1 (acidic)
  • Gene Summary:
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000066028,OTTHUMP00000066030,OTTHUMP00000066031,OTTHUMP00000174675,endothelial cell growth factor, alpha,endothelial cell growth factor, beta,heparin-binding growth factor 1
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