Product Browser

Last updated: 2014/8/25

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CCL2 (Human) Recombinant ProteinBioActive

  • Catalog # : P3647
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human CCL2 (P13500, 24 a.a. - 99 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • QPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 9
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Ion exchange column and HPLC reverse phase column
  • Purity:
  • > 98% by SDS-PAGE and HPLC
  • Endotoxin Level:
  • < 0.1 ng/ug (1 EU/ug)
  • Activity:
  • Determined by its ability to chemoattract human monocytes using a concentration range of 2.0-40.0 ng/mL.
  • Storage Buffer:
  • Lyophilized from 0.02 M Tris-HCl, pH 7.5 (20% glycerol)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 6347
  • Gene Name:
  • CCL2
  • Gene Alias:
  • GDCF-2,HC11,HSMCR30,MCAF,MCP-1,MCP1,MGC9434,SCYA2,SMC-CF
  • Gene Description:
  • chemokine (C-C motif) ligand 2
  • Gene Summary:
  • This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq
  • Other Designations:
  • monocyte chemoattractant protein-1,monocyte chemotactic and activating factor,monocyte chemotactic protein 1, homologous to mouse Sig-je,monocyte secretory protein JE,small inducible cytokine A2,small inducible cytokine A2 (monocyte chemotactic protein 1,
  • Related Disease
  • RSS
  • YouTube
  • Linkedin
  • Facebook