IFNB1 (Human) Recombinant Protein
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Specifications
Product Description
Human IFNB1 (P01574, 22 a.a. - 187 a.a.) partial recombinant protein expressed in CHO cells.
Sequence
MSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
Host
Mammals
Theoretical MW (kDa)
19
Form
Lyophilized
Preparation Method
Mammalian cell (CHO) expression system
Purification
Ion exchange column and HPLC reverse phase column
Purity
> 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug (1 EU/ug)
Activity
The activity was determined by the viral resistance assay of Human WISH cells was found to be in the range of 3 x 108 IU/mg.
Storage Buffer
Lyophilized from sodium acetate solution pH 4.8
Storage Instruction
Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IFNB1
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Interactomes
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Pathways
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Diseases
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Publication Reference
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A fully human monoclonal antibody with novel binding epitope and excellent neutralizing activity to multiple human IFN-α subtypes: a candidate therapy for systemic lupus erythematosus.
Du P, Xu L, Qiu W, Zeng D, Yue J, Wang S, Huang P, Sun Z.
MAbs 2015 Sep; 7(5):969.
Application:Func, Purified AIA22.
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A fully human monoclonal antibody with novel binding epitope and excellent neutralizing activity to multiple human IFN-α subtypes: a candidate therapy for systemic lupus erythematosus.
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