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IL2 (Human) Recombinant ProteinBioActive

  • Catalog # : P3455
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  • Specification
  • Product Description:
  • Human IL2 (NP_000577, 22 a.a. - 153 a.a.) partial recombinant protein expressed in Escherichia coli.
  • Sequence:
  • MPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 15.4
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purification:
  • Conventional Chromatography
  • Concentration:
  • 0.5 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Activity:
  • Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 1.5 ng/mL.
  • Quality Control Testing:
  • Loading 3 ug protein in 15% SDS-PAGE

    QC Testing of P3455
  • Storage Buffer:
  • In PBS, pH 7.4
  • Storage Instruction:
  • Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3558
  • Gene Name:
  • IL2
  • Gene Alias:
  • IL-2,TCGF,lymphokine
  • Gene Description:
  • interleukin 2
  • Gene Summary:
  • The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq
  • Other Designations:
  • T cell growth factor,aldesleukin,interleukin-2,involved in regulation of T-cell clonal expansion
  • Related Disease
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