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Last updated: 2014/10/27

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ABCG2 (C-term) Peptide

  • Catalog # : P0483
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  • Specification
  • Product Description:
  • This synthetic peptide sequence is selected from human ABCG2 construct and is used as the immunogen for PAB3158.
  • Sequence:
  • C terminus of Human ABCG2
  • Form:
  • Lyophilized with 100% acetonitrile
  • Storage Buffer:
  • Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at-20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product is for research use only. Not for use in diagnostics or therapeutics.
  • Applications
  • Blocking
  • Application Image
  • Blocking
  • Gene Information
  • Entrez GeneID:
  • 9429
  • Protein Accession#:
  • NP_004818;Q9UNQ0
  • Gene Name:
  • ABCG2
  • Gene Alias:
  • ABC15,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,MGC102821,MRX,MXR,MXR1
  • Gene Description:
  • ATP-binding cassette, sub-family G (WHITE), member 2
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
  • Other Designations:
  • ABC transporter,ATP-binding cassette transporter G2,ATP-binding cassette, sub-family G, member 2,breast cancer resistance protein,mitoxantrone resistance protein,placenta specific MDR protein
  • Gene Pathway
  • Related Disease
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