AKR1B1 monoclonal antibody, clone 1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant AKR1B1.
Immunogen
Recombinant protein corresponding to amino acids 33-316 of human AKR1B1.
Host
Mouse
Reactivity
Human
Specificity
It can expression in Jurkat whole cell lysate.
Form
Liquid
Purification
Affinity purification
Isotype
IgG2b
Recommend Usage
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of Jurkat whole cell lystae with AKR1B1 monoclonal antibody, clone 1 (Cat # MAB9984) at 1:1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AKR1B1
Entrez GeneID
231Protein Accession#
P15121Gene Name
AKR1B1
Gene Alias
ADR, ALDR1, ALR2, AR, MGC1804
Gene Description
aldo-keto reductase family 1, member B1 (aldose reductase)
Omim ID
103880Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq
Other Designations
Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1, member B1|aldose reductase|low Km aldose reductase
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Disease
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