KRT8 monoclonal antibody, clone 19
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of recombinant KRT8 protein with KRT8 monoclonal antibody, clone 19 (Cat # MAB9944) at 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) stain of human colon carcinoma tissue section with KRT8 monoclonal antibody, clone 19 (Cat # MAB9944) at 1:1000 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant KRT8.
Immunogen
Recombinant protein corresponding to full length human KRT8.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG2b
Recommend Usage
Western blot (1:1000)
Immunohistochemistry (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western Blot (Recombinant protein)
Western blot analysis of recombinant KRT8 protein with KRT8 monoclonal antibody, clone 19 (Cat # MAB9944) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) stain of human colon carcinoma tissue section with KRT8 monoclonal antibody, clone 19 (Cat # MAB9944) at 1:1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KRT8
Entrez GeneID
3856GeneBank Accession#
NM_002273Protein Accession#
NP_002264Gene Name
KRT8
Gene Alias
CARD2, CK8, CYK8, K2C8, K8, KO
Gene Description
keratin 8
Gene Ontology
HyperlinkGene Summary
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
Other Designations
cytokeratin 8|keratin, type II cytoskeletal 8
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Interactome
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Disease
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