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TNF monoclonal antibody, clone 4E1

  • Catalog # : MAB9938
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant TNF.
  • Immunogen:
  • Recombinant protein corresponding to full length human TNF.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western blot (1:1000)
    Immunohistochemistry (1:10)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of recombinant TNF protein with TNF monoclonal antibody, clone 4E1 (Cat # MAB9938) at 1:1000 dilution.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human liver cancer tissue section with TNF monoclonal antibody, clone 4E1 (Cat # MAB9938) at 1:10 dilution.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7124
  • Gene Name:
  • TNF
  • Gene Alias:
  • DIF,TNF-alpha,TNFA,TNFSF2
  • Gene Description:
  • tumor necrosis factor (TNF superfamily, member 2)
  • Gene Summary:
  • This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
  • Other Designations:
  • APC1 protein,OTTHUMP00000029281,OTTHUMP00000037669,TNF superfamily, member 2,TNF, macrophage-derived,TNF, monocyte-derived,cachectin,tumor necrosis factor alpha
  • Related Disease
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