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IL1B monoclonal antibody, clone 2H12

  • Catalog # : MAB9933
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant IL1B.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 118-269 of human IL1B.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western blot (1:1000)
    Immunohistochemistry (1:10)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of recombinant IL1B protein with IL1B monoclonal antibody, clone 2H12 (Cat # MAB9933) at 1:1000 dilution.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human liver cancer tissue section with IL1B monoclonal antibody, clone 2H12 (Cat # MAB9933) at 1:10 dilution.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3553
  • Gene Name:
  • IL1B
  • Gene Alias:
  • IL-1,IL1-BETA,IL1F2
  • Gene Description:
  • interleukin 1, beta
  • Gene Summary:
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
  • Other Designations:
  • catabolin,preinterleukin 1 beta,pro-interleukin-1-beta
  • Interactome
  • Interactome
  • Related Disease
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