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Last updated: 2014/7/21
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PDGFRB monoclonal antibody, clone 18A2 (PE)

  • Catalog # : MAB9802
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant PDGFRB.
  • Immunogen:
  • Recombinant protein corresponding to full length human PDGFRB.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 180-190
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody 18A2 recognizes PDGFRB (CD140b), the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Purification:
  • Size-exclusion chromatography purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% BSA, 15 mM sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 5159
  • Gene Name:
  • PDGFRB
  • Gene Alias:
  • CD140B,JTK12,PDGF-R-beta,PDGFR,PDGFR1
  • Gene Description:
  • platelet-derived growth factor receptor, beta polypeptide
  • Gene Summary:
  • This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
  • Other Designations:
  • beta platelet-derived growth factor receptor,platelet-derived growth factor receptor beta,soluble PDGFRb variant 1
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