SELL monoclonal antibody, clone DREG56 (FITC)
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Specification
Product Description
Mouse monoclonal antibody raised against native SELL.
Immunogen
Native purified SELL from PMA-activated human peripheral blood leukocytes.
Host
Mouse
Theoretical MW (kDa)
65-76
Reactivity
Human
Specificity
The mouse monoclonal antibody DREG56 recognizes SELL (CD62L / L-selectin), a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
Form
Liquid
Conjugation
FITC
Isotype
IgG1
Recommend Usage
Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.02% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — SELL
Entrez GeneID
6402Gene Name
SELL
Gene Alias
CD62L, LAM-1, LAM1, LECAM1, LNHR, LSEL, LYAM1, Leu-8, Lyam-1, PLNHR, TQ1, hLHRc
Gene Description
selectin L
Gene Ontology
HyperlinkGene Summary
SELL is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. [provided by RefSeq
Other Designations
Leu-8 antigen|leukocyte adhesion molecule-1|lymph node homing receptor|lymphocyte adhesion molecule 1
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Interactome
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Pathway
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Disease
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