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KRT19 monoclonal antibody, clone E16-L

  • Catalog # : MAB9770
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of KRT19.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human KRT19.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM Tris-HCl, pH 8.0 (20 mg/mL BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human tonsil tissue (A, 4 µm), human colon adenocarcinoma (B, 4 µm), and human liver tissue (C, 4 µm), stained with KRT19 monoclonal antibody, clone E16-L (Cat # MAB9770) shows strong positive cytoplasmic immunostaining of the squamous epithelial cells (A), strong positive cytoplasmic immunostaining of the neoplastic cells (B), and positive cytoplasmic immunostaining of the bile duct epithelial cells (C).
    Kindly performed and provided by Katarina Poliakova, MD and L'ubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovak republic.
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 3880
  • Gene Name:
  • KRT19
  • Gene Alias:
  • CK19,K19,K1CS,MGC15366
  • Gene Description:
  • keratin 19
  • Gene Summary:
  • The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq
  • Other Designations:
  • 40-kDa keratin intermediate filament,cytokeratin 19,keratin, type I cytoskeletal 19,keratin, type I, 40-kd
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