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Last updated: 2014/10/27
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TNFRSF8 monoclonal antibody, clone JCM182

  • Catalog # : MAB9664
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TNFRSF8.
  • Immunogen:
  • Recombinant protein corresponding to internal region of human TNFRSF8.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (15 mM sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining for paraffin-embedded Hodgkin's lymphoma section using TNFRSF8 monoclonal antibody, clone JCM182 (Cat # MAB9664). Note membrane and characteristic staining of paranuclear hofs of Reed Sternberg cells.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 943
  • Gene Name:
  • TNFRSF8
  • Gene Alias:
  • CD30,D1S166E,KI-1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • CD30 antigen,CD30L receptor,Ki-1 antigen,OTTHUMP00000001783,cytokine receptor CD30,lymphocyte activation antigen CD30
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