Product Browser

Last updated: 2014/4/14
  • Related Product Showcase
  • By Research Area

  • By Biomarker

Product Compare

Product Compare Cancel   Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location
BIOtech
BULK-new

MCM7 monoclonal antibody, clone DCS-141.1

  • Catalog # : MAB9653
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant MCM7.
  • Immunogen:
  • Recombinant protein corresponding to full length of human MCM7.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (1:25-1:50)
    Western Blot (1:25-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from tissue culture supernatant (15 mM sodium azide)
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with steril distilled water, Store at 4°C for at least two months.
    For long term storage store at -20°C or below.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining for paraffin-embedded human gastric carcinoma section using MCM7 monoclonal antibody, clone DCS-141.1 (Cat # MAB9653). Note intense nuclear staining of proliferating tumor cells.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4176
  • Gene Name:
  • MCM7
  • Gene Alias:
  • CDABP0042,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS-146
  • Gene Description:
  • minichromosome maintenance complex component 7
  • Gene Summary:
  • The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • DNA replication licensing factor MCM7,MCM7 minichromosome maintenance deficient 7,homolog of S. cerevisiae Cdc47,minichromosome maintenance deficient 7
  • Interactome
  • RSS
  • YouTube
  • Linkedin
  • Facebook