Mouse monoclonal antibody raised against synthetic phosphopeptide of MAPT.
Synthetic phosphopeptide corresponding to residues surrounding S199 of human MAPT.
This antibody specifically detects phosphorylated protein derived from human brain tissue. It recognizes PHF-tau phosphorylated at Ser199 in both ELISA and WB. This antibody shows no cross-reactivity with other unrelated protein.
ELISA (1:1000-1:2000) Western Blot (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Lyophilized from PBS, pH 7.5, 0.1% BSA.
Store at -20°C. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq
G protein beta1/gamma2 subunit-interacting factor 1,microtubule-associated protein tau, isoform 4