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Last updated: 2014/4/14
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BIOtech
BULK-new

LTA monoclonal antibody, clone AT15A3

  • Catalog # : MAB8481
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant LTA.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 35-205 of human LTA.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Western Blot (1:250-1:500)
    Immunofluorescence (1:250-1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.1% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Tissue lysates of mouse spleen (35 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with LTA monoclonal antibody, clone AT15A3 (Cat # MAB8481) (1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence of human HeLa cells stained with LTA monoclonal antibody, clone AT15A3 (Cat # MAB8481) (1 : 500) with Texas Red (Red). Nucleus was stained by Hoechst 33342 (Blue).
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4049
  • Gene Name:
  • LTA
  • Gene Alias:
  • LT,TNFB,TNFSF1
  • Gene Description:
  • lymphotoxin alpha (TNF superfamily, member 1)
  • Gene Summary:
  • The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis
  • Other Designations:
  • OTTHUMP00000029184,OTTHUMP00000037612,OTTHUMP00000037613,OTTHUMP00000165897,lymphotoxin alpha,tumor necrosis factor beta
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