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BIOtech
BULK-new

CASP2 monoclonal antibody, clone SB123a1

  • Catalog # : MAB8215
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against native CASP2.
  • Immunogen:
  • Native purified human CASP2.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgM
  • Recommend Usage:
  • Western Blot (1-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 100 mM BBS, pH 8.0
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Jurkat cells stimulated with anti-DR5antibody. Cell lysate was stained with CASP2 monoclonal antibody, clone SB123a1 (Cat # MAB8215). HRP-conjugatedGoat anti-Rat IgM was used to develop.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 835
  • Gene Name:
  • CASP2
  • Gene Alias:
  • CASP-2,ICH-1L,ICH-1L/1S,ICH1,NEDD2
  • Gene Description:
  • caspase 2, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq
  • Other Designations:
  • ICH-1 protease,NEDD2 apoptosis regulatory,caspase 2,neural precursor cell expressed, developmentally down-regulated 2
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