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Last updated: 2014/12/21
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LAMA5 monoclonal antibody, clone 4B12

  • Catalog # : MAB7872
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native LAMA5.
  • Immunogen:
  • Native purified human placenta LAMA5.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Laminin purified from human placenta (Chemicon).
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:64000)
    Immunoprecipitation (1:20)
    Immunohistochemistry (1:100-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.1% sodium azide)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining on human embryonic lung alveolae epithelium (A) and kidney (B) with LAMA5 monoclonal antibody, clone 4B12 (Cat # MAB7872).
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3911
  • Gene Name:
  • LAMA5
  • Gene Alias:
  • KIAA1907
  • Gene Description:
  • laminin, alpha 5
  • Gene Summary:
  • Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq
  • Other Designations:
  • laminin alpha 5,laminin alpha-5 chain
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