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Last updated: 2014/9/29
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PSAP monoclonal antibody, clone PASE/4LJ

  • Catalog # : MAB7070
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native PSAP.
  • Immunogen:
  • Native purified human PSAP.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This is specific to human prostatic acid phosphatase. It reacts with the glandular epithelium of normal and hyperplastic prostate and with prostate adenocarcinoma. It does not show any cross-reactivity with PSAP from dog, rabbit and rat. Does not react with Dog, Rabbit or Rat.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunohistochemistry (1:25-1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In buffer containing sodium azide
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin fixed paraffin of human prostate with PSAP monoclonal antibody, clone PASE/4LJ (Cat # MAB7070).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 5660
  • Gene Name:
  • PSAP
  • Gene Alias:
  • FLJ00245,GLBA,MGC110993,SAP1
  • Gene Description:
  • prosaposin
  • Gene Summary:
  • This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019776,sphingolipid activator protein-1
  • Gene Pathway
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