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- Home > Products > Monoclonal Ab > Human > Plasma/Serum > PSAP monoclonal antibody, clone PASE/4LJ
PSAP monoclonal antibody, clone PASE/4LJ
- Catalog # : MAB7070
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- 500 uL
- USD $ 415
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native PSAP.
- Immunogen:
- Native purified human PSAP.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This is specific to human prostatic acid phosphatase. It reacts with the glandular epithelium of normal and hyperplastic prostate and with prostate adenocarcinoma. It does not show any cross-reactivity with PSAP from dog, rabbit and rat. Does not react with Dog, Rabbit or Rat.
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Recommend Usage:
- Immunohistochemistry (1:25-1:100)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In buffer containing sodium azide
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Small cell carcinoma of the esophagus: a case report.
Hatori S, Imada T, Rino Y, Takahashi M, Amano T, Kondo J.Hepatogastroenterology. 1999 May-Jun;46(27):1788-90.
- 2.
- A novel hybridoma antibody (PASE/4LJ) to human prostatic acid phosphatase suitable for immunohistochemistry.
Haines AM, Larkin SE, Richardson AP, Stirling RW, Heyderman E.Br J Cancer. 1989 Dec;60(6):887-92.
- Entrez GeneID:
- 5660
- Gene Name:
- PSAP
- Gene Alias:
- FLJ00245,GLBA,MGC110993,SAP1
- Gene Description:
- prosaposin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- OTTHUMP00000019776,sphingolipid activator protein-1
- Gene Pathway
