Mouse monoclonal antibody raised against native PSAP.
Native purified human PSAP.
This is specific to human prostatic acid phosphatase. It reacts with the glandular epithelium of normal and hyperplastic prostate and with prostate adenocarcinoma. It does not show any cross-reactivity with PSAP from dog, rabbit and rat. Does not react with Dog, Rabbit or Rat.
Immunohistochemistry (1:25-1:100) The optimal working dilution should be determined by the end user.
In buffer containing sodium azide
Store at 4°C. Do not freeze.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq