HLA-DRA monoclonal antibody, clone TAL 1B5
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against HLA-DRA.
Immunogen
Human bristol 8 separated alpha chain preparation
Host
Mouse
Reactivity
Human
Specificity
HLA DR (TAL 1B5). Western blots to dimer and DR alpha chain. MW 33KDa.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — HLA-DRA
Entrez GeneID
3122Gene Name
HLA-DRA
Gene Alias
HLA-DRA1
Gene Description
major histocompatibility complex, class II, DR alpha
Omim ID
142860Gene Ontology
HyperlinkGene Summary
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq
Other Designations
HLA class II histocompatibility antigen, DR alpha chain|MHC cell surface glycoprotein|histocompatibility antigen HLA-DR alpha
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.
Adams TE, Bodmer JG, Bodmer WF.
Immunology 1983 Dec; 50(4):613.
Application:IP, Recombinant protein.
-
Production and characterization of monoclonal antibodies recognizing the alpha-chain subunits of human ia alloantigens.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com