SELL monoclonal antibody, clone LAM1-116
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native SELL.
Immunogen
Native purified SELL from mouse pre-B cells expressing human L-selectin.
Host
Mouse
Reactivity
Human
Specificity
Antibody LAM1-116 blocks CD62L function and induces expression of beta-1 and beta-2 integrins.
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
-
Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
-
Gene Info — SELL
Entrez GeneID
6402Gene Name
SELL
Gene Alias
CD62L, LAM-1, LAM1, LECAM1, LNHR, LSEL, LYAM1, Leu-8, Lyam-1, PLNHR, TQ1, hLHRc
Gene Description
selectin L
Gene Ontology
HyperlinkGene Summary
SELL is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. [provided by RefSeq
Other Designations
Leu-8 antigen|leukocyte adhesion molecule-1|lymph node homing receptor|lymphocyte adhesion molecule 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Ligation of L-selectin through conserved regions within the lectin domain activates signal transduction pathways and integrin function in human, mouse, and rat leukocytes.
Steeber DA, Engel P, Miller AS, Sheetz MP, Tedder TF.
Journal of Immunology 1997 Jul; 159(2):952.
Application:Flow Cyt, Func, Human, Mouse, Rat, Leukocytes.
-
Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration.
Springer TA.
Annual Review of Physiology 1995 Jan; 57:827.
Application:Flow Cyt, IA, Human, Mouse, Leukocytes, Neutrophils.
-
Ligation of L-selectin through conserved regions within the lectin domain activates signal transduction pathways and integrin function in human, mouse, and rat leukocytes.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com