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- Home > Products > Monoclonal Ab > Human > Membrane > Receptor > CD74 monoclonal antibody, clone PIN.1
CD74 monoclonal antibody, clone PIN.1
- Catalog # : MAB6623
- Visit Frequency :
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- 100 ug
- USD $ 335
- order now, ship in 5 days
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of CD74.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to invariant chain of human CD74.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Detects~33-35KDa protein doublet corresponding to the molecular mass of the p33 and p35 forms of human CD74 on SDS PAGE immunoblots.
- Form:
- Liquid
- Isotype:
- IgG
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS, pH 7.2 (50% glycerol, 0.09% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cell-surface CD74 initiates a signaling cascade leading to cell proliferation and survival.
Starlets D, Gore Y, Binsky I, Haran M, Harpaz N, Shvidel L, Becker-Herman S, Berrebi A, Shachar I.Blood. 2006 Jun 15;107(12):4807-16. Epub 2006 Feb 16.
- 2.
- CD74 is a member of the regulated intramembrane proteolysis-processed protein family.
Becker-Herman S, Arie G, Medvedovsky H, Kerem A, Shachar I.Mol Biol Cell. 2005 Nov;16(11):5061-9. Epub 2005 Aug 17.
- 3.
- Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells.
Denzin LK, Robbins NF, Carboy-Newcomb C, Cresswell P.Immunity. 1994 Oct;1(7):595-606.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunocytochemistry
- Immunoprecipitation
- Flow Cytometry
- Entrez GeneID:
- 972
- Gene Name:
- CD74
- Gene Alias:
- DHLAG,HLADG,Ia-GAMMA
- Gene Description:
- CD74 molecule, major histocompatibility complex, class II invariant chain
- Omim ID:
- 142790
- Gene Ontology:
- Hyperlink
- Other Designations:
- CD74 antigen,CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated),HLA-DR-gamma,Ia-associated invariant chain,MHC HLA-DR gamma chain,gamma chain of class II antigens
- Gene Pathway
- Related Disease
