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Last updated: 2014/10/27
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PTPN6 monoclonal antibody, clone PTY15

  • Catalog # : MAB6402
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant PTPN6.
  • Immunogen:
  • Recombinant protein corresponding to full length human PTPN6.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 67
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes single 67 KDa PTPN6 in human cells that express the enzyme and the SH2(C) domain.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 10 mM PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C.
    Aliquot after reconstitution to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunocytochemistry
  • ELISA
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5777
  • Gene Name:
  • PTPN6
  • Gene Alias:
  • HCP,HCPH,HPTP1C,PTP-1C,SH-PTP1,SHP-1,SHP-1L,SHP1
  • Gene Description:
  • protein tyrosine phosphatase, non-receptor type 6
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq
  • Other Designations:
  • hematopoietic cell phosphatase,hematopoietic cell protein-tyrosine phosphatase,protein-tyrosine phosphatase 1C
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